Recent Publications

Prakash R, Goodlett DW, Varghese S, Andrys J, Gbadamosi FA, Arriaza RH, Patel M, Tiwari PB, Borowski T, Chruszcz M, Shimizu LS, Upadhyay G.Development of fluorophore labeled or biotinylated anticancer small molecule NSC243928. Bioorg Med Chem. 2023. PMID: 36680947

Välikangas T, Suomi T, Chandler CE, Scott AJ, Tran BQ, Ernst RK, Goodlett DR, Elo LL.Benchmarking tools for detecting longitudinal differential expression in proteomics data allows establishing a robust reproducibility optimization regression approach. Nat Commun. 2022. PMID: 36550114

Sherman ME, Smith RD, Gardner FM, Goodlett DR, Ernst RK.A Sensitive GC-MS Method for Quantitation of Lipid A Backbone Components and Terminal Phosphate Modifications. J Am Soc Mass Spectrom. 2022. PMID: 36326685

Yang H, Smith RD, Sumner KP, Goodlett DR, Johnson JK, Ernst RK.A Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry Direct-from-Urine-Specimen Diagnostic for Gram-Negative Pathogens. Microbiol Spectr. 2022. PMID: 36255333

Zik JJ, Yoon SH, Guan Z, Stankeviciute Skidmore G, Gudoor RR, Davies KM, Deutschbauer AM, Goodlett DR, Klein EA, Ryan KR.Caulobacter lipid A is conditionally dispensable in the absence of fur and in the presence of anionic sphingolipids. Cell Rep. 2022. PMID: 35649364

Rocheleau GLY, Lee T, Mohammed Y, Goodlett D, Burns K, Cheng MP, Tran K, Sweet D, Marshall J, Slutsky AS, Murthy S, Singer J, Patrick DM, Du B, Peng Z, Lee TC, Boyd JH, Walley KR, Lamontagne F, Fowler R, Winston BW, Haljan G, Vinh DC, McGeer A, Maslove D, Patrigeon SP, Mann P, Donohoe K, Hernandez G, Russell JA.Renin-Angiotensin System Pathway Therapeutics Associated With Improved Outcomes in Males Hospitalized With COVID-19. Crit Care Med. 2022. PMID: 35607951

Yang H, Smith RD, Chandler CE, Johnson JK, Jackson SN, Woods AS, Scott AJ, Goodlett DR, Ernst RK.Lipid A Structural Determination from a Single Colony. Anal Chem. 2022. PMID: 35576511

Weke K, Kote S, Faktor J, Al Shboul S, Uwugiaren N, Brennan PM, Goodlett DR, Hupp TR, Dapic I.DIA-MS proteome analysis of formalin-fixed paraffin-embedded glioblastoma tissues. Anal Chim Acta. 2022. PMID: 35397901

Doerfler AM, Han J, Jarrett KE, Tang L, Jain A, Saltzman A, De Giorgi M, Chuecos M, Hurley AE, Li A, Morand P, Ayala C, Goodlett DR, Malovannaya A, Martin JF, de Aguiar Vallim TQ, Shroyer N, Lagor WR.Intestinal Deletion of 3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase Promotes Expansion of the Resident Stem Cell Compartment. Arterioscler Thromb Vasc Biol. 2022. PMID: 35172604

Dapic I, Uwugiaren N, Kers J, Mohammed Y, Goodlett DR, Corthals G.Evaluation of Fast and Sensitive Proteome Profiling of FF and FFPE Kidney Patient Tissues. Molecules. 2022. PMID: 35164409

Mohammed Y, Goodlett DR, Cheng MP, Vinh DC, Lee TC, Mcgeer A, Sweet D, Tran K, Lee T, Murthy S, Boyd JH, Singer J, Walley KR, Patrick DM, Quan C, Ismail S, Amar L, Pal A, Bassawon R, Fesdekjian L, Gou K, Lamontagne F, Marshall J, Haljan G, Fowler R, Winston BW, Russell JA.Longitudinal Plasma Proteomics Analysis Reveals Novel Candidate Biomarkers in Acute COVID-19. J Proteome Res. 2022. PMID: 35143212

Smith RD, McElheny CL, Izac JR, Gardner FM, Chandler CE, Goodlett DR, Doi Y, Johnson JK, Ernst RK.A Novel Lipid-Based MALDI-TOF Assay for the Rapid Detection of Colistin-Resistant Enterobacter Species. Microbiol Spectr. 2022. PMID: 35107363

Mesa-Perez M, Hamilton PT, Miranda A, Brodie N, O'Sullivan C, Christie J, Ryan BC, Chow RL, Goodlett D, Nelson CJ, Howard PL.Cytoplasmic switch of ARS2 isoforms promotes nonsense-mediated mRNA decay and arsenic sensitivity. Nucleic Acids Res. 2022. PMID: 35104878

Froehlich BC, Gill HK, Joshi A, Goodlett DR.MS visualization and interpretation software (MS-VIS), a tool for visualizing mass spectra and analysing mass lists. Rapid Commun Mass Spectrom. 2022. PMID: 34997654

Harberts E, Liang T, Yoon SH, Opene BN, McFarland MA, Goodlett DR, Ernst RK.Correction to "Toll-like Receptor 4-Independent Effects of Lipopolysaccharide Identified Using Longitudinal Serum Proteomics". J Proteome Res. 2022. PMID: 34793171

Ernst O, Khan MM, Oyler BL, Yoon SH, Sun J, Lin FY, Manes NP, MacKerell AD Jr, Fraser IDC, Ernst RK, Goodlett DR, Nita-Lazar A.Species-Specific Endotoxin Stimulus Determines Toll-Like Receptor 4- and Caspase 11-Mediated Pathway Activation Characteristics. mSystems. 2021. PMID: 34342534

Pirog A, Faktor J, Urban-Wojciuk Z, Kote S, Chruściel E, Arcimowicz Ł, Marek-Trzonkowska N, Vojtesek B, Hupp TR, Al Shboul S, Brennan PM, Smoleński RT, Goodlett DR, Dapic I.Comparison of different digestion methods for proteomic analysis of isolated cells and FFPE tissue samples. Talanta. 2021. PMID: 34215064

Chattagul S, Khan MM, Scott AJ, Nita-Lazar A, Ernst RK, Goodlett DR, Sermswan RW.Transcriptomics Analysis Uncovers Transient Ceftazidime Tolerance in Burkholderia Biofilms. ACS Infect Dis. 2021. PMID: 34138549

Alfaro JA, Bohländer P, Dai M, Filius M, Howard CJ, van Kooten XF, Ohayon S, Pomorski A, Schmid S, Aksimentiev A, Anslyn EV, Bedran G, Cao C, Chinappi M, Coyaud E, Dekker C, Dittmar G, Drachman N, Eelkema R, Goodlett D, Hentz S, Kalathiya U, Kelleher NL, Kelly RT, Kelman Z, Kim SH, Kuster B, Rodriguez-Larrea D, Lindsay S, Maglia G, Marcotte EM, Marino JP, Masselon C, Mayer M, Samaras P, Sarthak K, Sepiashvili L, Stein D, Wanunu M, Wilhelm M, Yin P, Meller A, Joo C.The emerging landscape of single-molecule protein sequencing technologies. Nat Methods. 2021. PMID: 34099939

Kalathiya U, Padariya M, Faktor J, Coyaud E, Alfaro JA, Fahraeus R, Hupp TR, Goodlett DR.Interfaces with Structure Dynamics of the Workhorses from Cells Revealed through Cross-Linking Mass Spectrometry (CLMS). Biomolecules. 2021. PMID: 33806612

Gauthier AE, Chandler CE, Poli V, Gardner FM, Tekiau A, Smith R, Bonham KS, Cordes EE, Shank TM, Zanoni I, Goodlett DR, Biller SJ, Ernst RK, Rotjan RD, Kagan JC.Deep-sea microbes as tools to refine the rules of innate immune pattern recognition. Sci Immunol. 2021. PMID: 33712473

Bhowmick P, Roome S, Borchers CH, Goodlett DR, Mohammed Y.An Update on MRMAssayDB: A Comprehensive Resource for Targeted Proteomics Assays in the Community. J Proteome Res. 2021. PMID: 33683131

Goodlett DW, Sindt AJ, Hossain MS, Merugu R, Smith MD, Garashchuk S, Gudmundsdottir AD, Shimizu LS.From Incident Light to Persistent and Regenerable Radicals of Urea-Assembled Benzophenone Frameworks: A Structural Investigation. J Phys Chem A. 2021. PMID: 33534579

Weke K, Singh A, Uwugiaren N, Alfaro JA, Wang T, Hupp TR, O'Neill JR, Vojtesek B, Goodlett DR, Williams SM, Zhou M, Kelly RT, Zhu Y, Dapic I.MicroPOTS Analysis of Barrett's Esophageal Cell Line Models Identifies Proteomic Changes after Physiologic and Radiation Stress. J Proteome Res. 2021. PMID: 33491460

Bansal R, Khan MM, Dasari S, Verma I, Goodlett DR, Manes NP, Nita-Lazar A, Sharma SP, Kumar A, Singh N, Chakraborti A, Gupta V, Dogra MR, Ram J, Gupta A.Proteomic profile of vitreous in patients with tubercular uveitis. Tuberculosis (Edinb). 2021. PMID: 33359883

Sorensen M, Chandler CE, Gardner FM, Ramadan S, Khot PD, Leung LM, Farrance CE, Goodlett DR, Ernst RK, Nilsson E.Rapid microbial identification and colistin resistance detection via MALDI-TOF MS using a novel on-target extraction of membrane lipids. Sci Rep. 2020. PMID: 33299017

Yang H, Jackson SN, Woods AS, Goodlett DR, Ernst RK, Scott AJ.Streamlined Analysis of Cardiolipins in Prokaryotic and Eukaryotic Samples Using a Norharmane Matrix by MALDI-MSI. J Am Soc Mass Spectrom. 2020. PMID: 32924474

Yang H, Chandler CE, Jackson SN, Woods AS, Goodlett DR, Ernst RK, Scott AJ.On-Tissue Derivatization of Lipopolysaccharide for Detection of Lipid A Using MALDI-MSI. Anal Chem. 2020. PMID: 32902263

Chandler CE, Harberts EM, Pelletier MR, Thaipisuttikul I, Jones JW, Hajjar AM, Sahl JW, Goodlett DR, Pride AC, Rasko DA, Trent MS, Bishop RE, Ernst RK.Early evolutionary loss of the lipid A modifying enzyme PagP resulting in innate immune evasion in Yersinia pestis. Proc Natl Acad Sci U S A. 2020. PMID: 32868431

Faktor J, Grasso G, Zavadil Kokas F, Kurkowiak M, Mayordomo MY, Kote S, Singh A, Ruidong L, O'Neill JR, Muller P, Goodlett D, Vojtesek B, Hupp T.The effects of p53 gene inactivation on mutant proteome expression in a human melanoma cell model. Biochim Biophys Acta Gen Subj. 2020. PMID: 32866596

Srzentić K, Fornelli L, Tsybin YO, Loo JA, Seckler H, Agar JN, Anderson LC, Bai DL, Beck A, Brodbelt JS, van der Burgt YEM, Chamot-Rooke J, Chatterjee S, Chen Y, Clarke DJ, Danis PO, Diedrich JK, D'Ippolito RA, Dupré M, Gasilova N, Ge Y, Goo YA, Goodlett DR, Greer S, Haselmann KF, He L, Hendrickson CL, Hinkle JD, Holt MV, Hughes S, Hunt DF, Kelleher NL, Kozhinov AN, Lin Z, Malosse C, Marshall AG, Menin L, Millikin RJ, Nagornov KO, Nicolardi S, Paša-Tolić L, Pengelley S, Quebbemann NR, Resemann A, Sandoval W, Sarin R, Schmitt ND, Shabanowitz J, Shaw JB, Shortreed MR, Smith LM, Sobott F, Suckau D, Toby T, Weisbrod CR, Wildburger NC, Yates JR 3rd, Yoon SH, Young NL, Zhou M.Interlaboratory Study for Characterizing Monoclonal Antibodies by Top-Down and Middle-Down Mass Spectrometry. J Am Soc Mass Spectrom. 2020. PMID: 32812765

Sun D, Böhringer KF, Sorensen M, Nilsson E, Edgar JS, Goodlett DR.Droplet delivery and nebulization system using surface acoustic wave for mass spectrometry. Lab Chip. 2020. PMID: 32760973

Goodlett D, Hung A, Feriozzi A, Lu H, Bekelman JE, Mullins CD.Site engagement for multi-site clinical trials. Contemp Clin Trials Commun. 2020. PMID: 32685765

Ryu SY, Wendt GA, Ernst RK, Goodlett DR.MGMS2: Membrane glycolipid mass spectrum simulator for polymicrobial samples. Rapid Commun Mass Spectrom. 2020. PMID: 32384576

Zhou M, Uwugiaren N, Williams SM, Moore RJ, Zhao R, Goodlett D, Dapic I, Paša-Tolić L, Zhu Y.Sensitive Top-Down Proteomics Analysis of a Low Number of Mammalian Cells Using a Nanodroplet Sample Processing Platform. Anal Chem. 2020. PMID: 32374172

Benti S, Tiwari PB, Goodlett DW, Daneshian L, Kern GB, Smith MD, Uren A, Chruszcz M, Shimizu LS, Upadhyay G.Small Molecule Binds with Lymphocyte Antigen 6K to Induce Cancer Cell Death. Cancers (Basel). 2020. PMID: 32098321

Harberts E, Liang T, Yoon SH, Opene BN, McFarland MA, Goodlett DR, Ernst RK.Toll-like Receptor 4-Independent Effects of Lipopolysaccharide Identified Using Longitudinal Serum Proteomics. J Proteome Res. 2020. PMID: 32037835

Sindt AJ, DeHaven BA, Goodlett DW, Hartel JO, Ayare PJ, Du Y, Smith MD, Mehta AK, Brugh AM, Forbes MDE, Bowers CR, Vannucci AK, Shimizu LS.Guest Inclusion Modulates Concentration and Persistence of Photogenerated Radicals in Assembled Triphenylamine Macrocycles. J Am Chem Soc. 2020. PMID: 31814397

Urban-Wojciuk Z, Khan MM, Oyler BL, Fåhraeus R, Marek-Trzonkowska N, Nita-Lazar A, Hupp TR, Goodlett DR.The Role of TLRs in Anti-cancer Immunity and Tumor Rejection. Front Immunol. 2019. PMID: 31695691

Dapic I, Baljeu-Neuman L, Uwugiaren N, Kers J, Goodlett DR, Corthals GL.Proteome analysis of tissues by mass spectrometry. Mass Spectrom Rev. 2019. PMID: 31390493

Ryu SY, Wendt GA, Chandler CE, Ernst RK, Goodlett DR.Model-Based Spectral Library Approach for Bacterial Identification via Membrane Glycolipids. Anal Chem. 2019. PMID: 31369253

Kote S, Faktor J, Dapic I, Mayordomo MY, Kocikowski M, Kagansky A, Goodlett D, Vojtesek B, Hupp T, Wilcockson D, Piper R.Analysis of venom sac constituents from the solitary, aculeate wasp Cerceris rybyensis. Toxicon. 2019. PMID: 31352010

Khan MM, Ernst O, Manes NP, Oyler BL, Fraser IDC, Goodlett DR, Nita-Lazar A.Multi-Omics Strategies Uncover Host-Pathogen Interactions. ACS Infect Dis. 2019. PMID: 30857388

Khan MM, Chattagul S, Tran BQ, Freiberg JA, Nita-Lazar A, Shirtliff ME, Sermswan RW, Ernst RK, Goodlett DR.Temporal proteomic profiling reveals changes that support Burkholderia biofilms. Pathog Dis. 2019. PMID: 30759239

Homayounfar N, Khan MM, Ji Y, Khoury ZH, Oates TW, Goodlett DR, Chellaiah M, Masri R.The effect of embryonic origin on the osteoinductive potential of bone allografts. J Prosthet Dent. 2019. PMID: 30598313

Liang T, Leung LM, Opene B, Fondrie WE, Lee YI, Chandler CE, Yoon SH, Doi Y, Ernst RK, Goodlett DR.Rapid Microbial Identification and Antibiotic Resistance Detection by Mass Spectrometric Analysis of Membrane Lipids. Anal Chem. 2019. PMID: 30571097

Leung LM, McElheny CL, Gardner FM, Chandler CE, Bowler SL, Mettus RT, Spychala CN, Fowler EL, Opene BNA, Myers RA, Goodlett DR, Doi Y, Ernst RK.A Prospective Study of Acinetobacter baumannii Complex Isolates and Colistin Susceptibility Monitoring by Mass Spectrometry of Microbial Membrane Glycolipids. J Clin Microbiol. 2019. PMID: 30567747

Fondrie WE, Liang T, Oyler BL, Leung LM, Ernst RK, Strickland DK, Goodlett DR.Pathogen Identification Direct From Polymicrobial Specimens Using Membrane Glycolipids. Sci Rep. 2018. PMID: 30367087

Schneider T, Oyler BL, Yoon SH, Liang T, Yen GS, Kilgour DPA, Nilsson E, Goodlett DR.Rapid Food Product Analysis by Surface Acoustic Wave Nebulization Coupled Mass Spectrometry. Food Anal Methods. 2018. PMID: 30271524

DeHaven BA, Goodlett DW, Sindt AJ, Noll N, De Vetta M, Smith MD, Martin CR, González L, Shimizu LS.Enhancing the Stability of Photogenerated Benzophenone Triplet Radical Pairs through Supramolecular Assembly. J Am Chem Soc. 2018. PMID: 30212205